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If you are heterozygous that means you have one affected gene and one normal gene

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accordingly, when a supramaximal dose (1 M) of exendin-4 (to fully activate remaining surface receptors) was added in addition to IBMX after prior incubation with each test agonist, a linear relationship between internalization and cAMP response was restored (Fig

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Provider judgment is essential in determining the optimal dose for each individual

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